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pentobarbital will lower the level or influence of osilodrostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital decreases levels of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent CYP3A4 inducers can lower panobinostat stages by ~70% and result in therapy failure.Check Closely (o

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